Hunan, China
Business Type:
Trading Company
Registered Capital:
510000 USD
Plant Area:
501~1000 square meters
Management System Certification:
ISO 9001, ISO 14064
Average Lead Time:
Peak season lead time: within 15 workdays
Off season lead time: within 15 workdays
OEM/ODM Service
Sample Available

Mangiferin, Formononetin, Mangiferin 98% manufacturer / supplier in China, offering High purity Healthy raw powder Mangiferin 4773-96-0, Local Anesthetic Drug Powder Benzocaine 99.8% pass UK customs, Local Anesthetic Powder Proca HCl in White Crystalline Powder and so on.

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High purity Healthy raw powder Mangiferin 4773-96-0

Min. Order / Reference FOB Price
10 grams US $4-7/ grams
Port: Hong Kong, Hong Kong
Production Capacity: 200kg/Month
Payment Terms: T/T, Western Union, Money Gram
Powder: Yes
Customized: Customized
Certification: ISO 9001, USP, BP
Suitable for: Adult
State: Solid
Purity: >99%

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Basic Info.

Model NO.
CAS: 4773-96-0
Assay
95%Min.
Appearance
Yellow Powder
Usage
Pharmaceutical Material
MF
C19H18O11
MW
422.34000
Supply ability
2000kg/month and more
Express
EMS, DHL, FedEx, etc(door-to-door) 
Delivery
24HS after payment received
Market
Global
Grade
Pharmaceutical Grade
Trademark
ZZYC
Transport Package
Foil Bag, or as Your Demand
Specification
1kg foil bag
Origin
China
High purity Healthy raw powder Mangiferin 4773-96-0

Product name: mangiferin
Alias: Hedysaride; hedysarid; chinonin; aphloiol; Mangiferin;
CAS number: 4773-96-0
Molecular formula: C19H18O11
Molecular weight: 422.34000
Exact mass: 422.08500
PSA: 201.28000

Appearance: light yellow powder
Density: 1.843 g/cm3
Melting point: 269-270ºC
Boiling point: 842.7oC at 760 mmHg
Flash point: 303.6ºC
Refractive index: 1.788

Dangerous goods transport code: UN 3462
Hazard category code: R28
Safety Instructions: S22-S28-S36 / 37-S45
Dangerous Goods Logo: T+


High purity Healthy raw powder Mangiferin 4773-96-0



Mangiferin COA:

Product name

Mangiferin

CAS No.

4773-96-0

Outer Packing

25kg

Production date

2017.12.20

Shelf life

2020.12.19

Standard adopted

Enterprise standard

Items of analysis

Specification

Results

(HPLC)Assay

≥98%

98.52%

Pesticides

Negative

Complies

Heavy metal

<10ppm

Complies

Appearance

Fine Power

Complies

Color

Pale yellow

Complies

Odor

Characteristic

Complies

Particle size

100% pass 80 mesh

Complies

Moisture

≤1.0%

0.35%

Total of bacteria

<1000/g

Complies

Fungi

<100/g

Complies

Salmonella

Negative

Complies

Coli

Negative

Complies

Conclusion

Qualified



Effects:
Central nervous system
Mangiferin has significant central nervous system excitation *, and all doses of 50-100 mg / kg of mangiferin intraperitoneally injected (jp) resulted in symptoms such as tremor, piloerection, forced tearing and increased autonomic activity. The peak of these behavioral changes was 30 minutes after administration and was maintained for 60 minutes and gradually decreased after 120 minutes. If the experimental animals pre-given chlorpromazine 5mg / kg, jp can block the role of mangiferin, indicating that mangiferin may be midbrain D2 receptor agonist system
When the experimental animals were given mangiferin 50mg/kg 30 minutes before Nembutal 30mg/kg,jp, jp could significantly prolong the sleep time of Nembutal, and the sleep time of rats first given mangiferin was(56.2_7.8) min and blank control group (36.2_5.3) min dose of mangiferin can significantly enhance the anesthetic effect of a mild anesthetic ether.In this dose range of 60% of mice lost normal reflex, while the blank control group No such phenomenon.
Respiratory system
Mangiferin on guinea pigs histamine, acetylcholine mixed with asthma significantly delayed the role of latent period of asthma; cough induced by ammonia in mice can significantly extend the latent period of cough, and significantly reduce the number of mice cough; acetic acid-induced intraperitoneal capillary Increased permeability there
Significant inhibition; tracheal phenol red excretion of mice significantly promote the role.
Cardiovascular
The 1-2mg dose of mangiferin has a transient, definite effect on the enhancement of myocardial contractility in normal or dysfunctional isolated Ringcrs perfused frog hearts, and this effect is not blocked by propranolol, so it may be Is a direct cardiac stimulant.
Antiviral
Mangiferin has the anti-herpes simplex virus type 1 (HSV-I) effect in vitro, with a plaque reduction rate of 56.8%. Its antiviral activity is attributed to its ability to inhibit intracellular viral replication.
Anti-radiation
Mangiferin is a natural antioxidant free radical scavenging, but also a natural radiation protective agent, the four phenolic hydroxyl groups in the molecular structure has electrophilic ability, and the benzene ring is a good energy trap, so that organisms Radiation-induced free radicals undergo molecular transfer to protect biological molecules.
Antitumor
In vivo or in vitro treatment of normal and tumor-bearing mice, mangiferin can increase the cytotoxicity of spleen cells and peritoneal macrophages.
Mangiferin can effectively reduce doxorubicin (Dox) inhibition of mitochondrial cytochrome C oxidase, and has no effect on the anti-tumor activity of Dox.
Anti-diabetic
After oral administration of mangiferin and its glucoside, normal mice blood glucose levels did not change, but can reduce the blood glucose concentration in spontaneous diabetic animal model KK-Ay mice, and serum ins levels also decreased.
Intraperitoneal injection of mangiferin significantly reduced the amount of glycosylated hemoglobin and serum creatine phosphokinase (CPK) in diabetic rats due to oxidative damage.
Liver protection
In the rat liver lysosome incubation experiment in vitro, it was found that mangiferin can stabilize the lysosomal membrane and directly inhibit the lysosome acid phosphatase activity.
other
Mangiferin still antibacterial; anti-inflammatory; fever and immune regulation role. Mangiferin pharmacological effects clear; a wide range of plant sources, the current clinical mainly for respiratory diseases.Although mangiferin due to poor solubility and other reasons make it greatly limited in clinical applications, but its anti-cancer; anti-virus and Anti-diabetic and other activities have attracted more and more attention. It is believed that with the deepening of research, mangiferin will have a good development prospect.
 

Competitive Advantage:


1. Our company is a professional production leading factory in China in pharmaceutical area of many years. Delivery areas of our products: US, UK, Canada, Australia, Brazil, Russia, Portugal, Latvia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium, Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Thailand, Israel and so on.
Payment method: T/T, Western union, Moneygram
 
2. Discreet package. The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also take into consideration.
 
3. Top quality. High quality guarenteed, once any problem is found, the package would be reshipped for you.
 
4. Security Shipping: Shipping by express (FedEx, UPS, DHL, EMS), by air. The most professional forwarder would be recommanded for you.
 
5. We have stock, so we can delivery quickly at the very day when receive the payment.
 
6. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.
 
7. A discount would be given when you make a large order.



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