5630-53-5 Anabolic Steroids Tibolona for Treatment of Endometriosis
|FOB Unit Price:||US $50 US $40|
|Purchase Qty. (g)||FOB Unit Price|
|Transport Package:||Special One, or as You Require|
|Payment Terms:||T/T, Western Union, Money Gram, Bitcoins|
- Model NO.: 5630-53-5
- Customized: Non-Customized
- Suitable for: Adult
- Purity: >99%
- Molecular Formula: C21h28o2
- Appearance: White Powder
- MOQ: 10g
- Trademark: muscle man
- Origin: China
- Powder: Yes
- Certification: ISO 9001
- State: Solid
- Assay: 99%Min
- Molecular Weight: 312.45
- Grade: Pharmaceutical Grade
- Einecs: 227-069-1
- Specification: EP
- HS Code: 2937290090
Synonyms: TIBOLONa; LIVIELLA; LIVIAL
Assay: 99% min.
Packing: 1kg/foil bag.
Delivery: Express courier.
Character: White powder.
Usage: Tibolona (INN, USAN, BAN) (brand name Livial, Tibofem) is a synthetic steroid drug with estrogenic, progestogenic, and weak androgenic actions which was introduced in 1988 and is used widely in Europe, Asia, Australasia, and, with the exception of the United States (where it is not available), the rest of the world. It is used mainly for treatment of endometriosis, as well as hormone replacement therapy in post-menopausal women. Tibolona has similar or greater efficacy compared to older hormone replacement drugs, but shares a similar side effect profile. It has also been investigated as a possible treatment for female sexual dysfunction.
Tibolona is a 19-nortestosterone derivative and is related structurally to other 19-nortestosterone progestins.
Tibolona possesses a complex pharmacology. Its two major active metabolites, 3a-hydroxytibolonand 3beta-hydroxytibolona, act as potent, fully activating agonists of the estrogen receptor (ER), with a high preference for ERa. Tibolonand its metabolite 4-tibolonact as agonists of the progesterone and androgen receptors, while 3beta-hydroxytibolonand 3beta-hydroxytibolon, conversely, act as antagonists of these receptors. Lastly, tibolona, 3α-hydroxytibolon, and 3beta-hydroxytibolonact as antagonists of the glucocorticoid and mineralocorticoid receptors, with preference for the mineralocorticoid receptor.
Tibolona has tissue-selective estrogenic effects, with desirable effects in bone, the brain, and the vagina, and lack of undesirable action in the endometrium and breasts. Its tissue selectivity is the result of metabolism, enzyme modulation (e.g., of estrogen sulfatase and estrogen sulfotransferase), and receptor modulation that vary in different target tissues, and differs mechanistically from that of selective estrogen receptor modulators (SERMs) such as which produce their tissue-selectivity via means of modulation of the ER. As such, to distinguish it from SERMs, tibolona has been described as a "selective tissue estrogenic activity regulator" (STEAR), and also as a "selective estrogen enzyme modulator" (SEEM).
Tag: china raw steroid powder supplier, steroid hormone manufacturer
1) Best prices with satisfied quality.
2) Rich experienced in delivering the parcels to you.
3) Enough stock ensure the prompt delivery time.
4) Good after-sales service.
5) Package will be reshipped if sent failed.
6) Specials are possible when the order is big enough.
Payment: western union, money gram, bitcoins, bank transfer.
Shipment: EMS, Fedex, DHL, TNT, UPS, Aramex and so on.
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Tracking number :
Send by EMS, the tracking number is availabe within 12 hours . The info would be trackable that day or 1 day later.
If send by HKEMS or other express,the tracking number would be provided next day. And this does not mean the info is trackable that day. It would be released on internet 2 or 3 days later . The reason why is that parcel should be shipped to Hongkong from forwarder then wait for the flight .
You sign for the parcel , deliveried.
We offer after-sales service after you receive parcel.
Any question, email me, I am Katharine.
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