Peptide Bremelanotide Powder PT-141 in Vials for Treating Sexual Disorders
|FOB Price:||US $10-20 / vials|
|Min. Order:||10 vials|
|Min. Order||FOB Price|
|10 vials||US $10-20/ vials|
|Production Capacity:||10000 Vials/Month|
|Payment Terms:||T/T, Western Union, Money Gram|
- Model NO.: CAS: 32780-32-8
- Customized: Customized
- State: Solid
- Name: Bremelanotide;PT-141
- Assay Purity: 99.4%Min.
- Payment: W/U, M/G, T/T, Bitcoin
- Trademark: Newman
- Specification: 99%
- Powder: Yes
- Suitable for: Research use
- Purity: >98%
- CAS: 32780-32-8
- MOQ: 10 Vials
- Shipment: The Parcel Will Arranged with 24 Hours
- Transport Package: Vials
- Origin: China
Single Impurity (HPLC):1.0%max
Amino Acid Composition:About 10% of theoretical
Peptide Content (N%):99% min.
Water Content(Karl Fischer):6.0%max.
Acetate Content (HPIC):15.0%max.
PT-141, commonly known as PT141 or Bremelanotide, is a synthetic heptapeptide analogue of the naturally occuring alpha-Melanocyte stimulating hormone (α-MSH) that is currently being studied for its numerous theoretical therapeutic applications. Alpha-MSH has potent influence over lipid metabolism, appetite, and sexual libido. PT-141 Bremelanotide, a metabolite of its predecessor Melanotan II, has the amino acid sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH and a molecular weight of 1025.2 Dalton. In initial testing, Melanotan II did induce melanogenesis, but additionally caused sexual arousal and spontaneous erections as unexpected side effects in nine out of the ten original male volunteer test subjects. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Resultantly, PT-141 has been shown in studies to exhibit libido-enhancing effects by activating melanocortin receptors. PT 141 has been researched extensively for its possible treatment of male sexual dysfunction (erectile dysfunction or impotence), female sexual dysfunction (sexual arousal disorder), hemorrhagic shock and reperfusion injury.
EFFECTS ON SEXUAL SOLICITATION IN RATS
Because female sexual dysfunction can be caused by a variety of physiological, personal and interpersonal triggers there are no pharmaceutical agents that can assist with this disorder, but research indicates that PT141 may have future use in this category.
In a recent study, PT141 was the focus of a study that addressed the reactions of this peptide in female rats.
PT141 binds to the central melanocortin receptors which will in turn selectively stimulate the solicitational behaviors exhibited by the female rat. It was revealed that these stimulations occurred independently of pacing, lordosis or other sexual behaviors.
The application of this chemical did not result in generalized motor activation or the rat's perception of the sexual reward.
This very selective effect on sexual behavior of female rats has not been reported in other similar studies. This implies that the central melanocortin systems may be important in the regulation of sexual desire in females and PT141 may be able to stimulate this area to help better manage disorders involving sexual desire.
Studies that study the varying effects of PT141 on male and female animal subjects are ongoing to help scientists better understand how this chemical affects natural hormones. Ongoing studies are also focusing on the potential side effects of these artificial chemicals may have when interacting with hormones and bodily produced chemicals within a natural setting.
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